Journal: Pharmaceutics

Article Title: Fabrication of Polypill Pharmaceutical Dosage Forms Using Fused Deposition Modeling 3D Printing: A Systematic Review

doi: 10.3390/pharmaceutics16101285

Figure Lengend Snippet: List of printed dosage forms with more than one API, inclusive of extrusion and printing details.

Article Snippet: Lisinopril dihydrate 10%, amlodipine besylate 5%, indapamide 2.5%, rosuvastatin calcium 10% , PEG 4000 10%, PEG 400 30% Shell: PLA for immediate release AND PVA for extended release , Lactose monohydrate , Ready PLA/PVA filaments , , , , Autodesk 3ds Max Design 2016 software version 18.0 (Autodesk, Inc., USA) , Makerbot Replicator 2X (Makerbot Industries, LLC, USA) , 200 °C , , , , , 50 °C , Capsule, oval , [ ] .

Techniques: Polymer, Software, Titanium Dioxide

Journal: Vaccines

Article Title: Overview of the Development, Impacts, and Challenges of Live-Attenuated Oral Rotavirus Vaccines

doi: 10.3390/vaccines8030341

Figure Lengend Snippet: Development and pre-clinical assessments of notable live-attenuated oral rotavirus vaccines.

Article Snippet: RotaSIIL ® (BRV-PV) , Pentavalent human–bovine reassortant serotypes G(1–4) and G9 , Serum Institute of India Pvt Ltd. (SIIPL). Presented in two forms–2.5 mL reconstituted lyophilised vial and 2.5 mL prepared liquid vial. Each scheduled as 3Ds , Pre-qualified for global use in 2018 but licensed for use in India since 2016. Co-administered with DPT 1, 2, and 3 vaccine doses , World’s first cost-effective, thermostable vaccine which can be stored without refrigeration or below 25 °C. It is a bovine UK rotavirus strain from NIH (USA), which was reassorted with human VP7 genome encoding segments [ ]. The vaccine has a lifespan of 20 months at 37 °C or 7 months at 45 °C. .

Techniques: Vaccines, Bioprocessing, Cell Culture, Modification, Immunopeptidomics, Isolation, Derivative Assay